Ritemed Celecoxib Contraindications

Hypersensitivity to any of the active substance or to any of the excipients.
Known hypersensitivity to sulphonamides.
Active peptic ulceration or gastrointestinal (GI) bleeding.
Patients who have experienced asthma, acute rhinitis, nasal polyps, angioneurotic edema, urticaria or other allergic-type reactions after taking acetylsalicylic acid (aspirin) or other non-steroidal anti-inflammatory drugs (NSAIDs) including COX-2 inhibitors.
In pregnancy and in women of childbearing potential unless using an effective method of contraception (see Use in Pregnancy & Lactation). Celecoxib has been shown to cause malformations in the two animal species studies (see Use in Pregnancy & Lactation and Pharmacology: Toxicology: Preclinical safety data under Actions). The potential for human risk in pregnancy is unknown, but cannot be excluded.
Breastfeeding (see Pharmacology: Toxicology: Preclinical safety data and Use in Pregnancy & Lactation).
Severe hepatic dysfunction (serum albumin <25 g/L or Child-Pugh score ≥10).
Patients with estimated creatinine clearance <30 mL/min.
Inflammatory bowel disease.
Congestive heart failure (NYHA II-IV).
Established ischaemic heart disease, peripheral arterial disease and/or cerebrovascular disease.